Hyperimmunoglobulin E (HIE) syndrome is a rare immunodeficiency disorder. HIE syndrome has multiple abnormalities include recurrent skin abscesses (hence, the name JOB syndrome), pneumonia, high serum levels of IgE, Facial, dental and skeletal features. We presented a case of HIE with dermatologic findings, recurrent productive cough and facial features. The diagnosis of HIE require differentiation from other disease. No definitive therapy is available for the treatment. The mainstay of treatment is the control of bacterial infections.

Introduction: JOB DESIGN approach is one of the significant concepts in ergonomics Experts believe that integration of macro ergonomics and JOB DESIGN can lead to improved productivity in the organizations. Therefore, this study examined the relationships between JOB DESIGN, performance and JOB satisfaction.Material and Method: This cross - sectional study was done in 11 branches of one of the bank in Hamadan. JOB DESIGN Questionnaire, JOB Satisfaction Questionnaires and Bank Performance Indicator were used in order to collect data. Spearman correlation coefficient was used for determining the correlation between each two variables.Result: This study showed that the motivational approach was the minimum approach (3.8%), and the mechanical approach was the dominant approach (74.7%) in the study branches and the majority of branches had an average level of JOB satisfaction. Moreover, there was a significant positive correlation between JOB DESIGN (motivational and cognitive approaches) and JOB satisfaction. In addition, the results showed that between JOB DESIGN (Motivational approach) and satisfaction were significantly correlated with performance, (p=0.05).Conclusion: Regarding the role of JOB DESIGN in JOB satisfaction and employees, performance, it can be stated that JOB reDESIGN towards a motivational approach and considering the principles of ergonomics in the workplace, can play an important role in efficiency and productivity of an organization.

Intracytoplasmic sperm injection (ICSI) is one of the most successful techniques of Assisted Reproductive Technology (ART) and is mostly in use for the treatment of infertility with male factors. In this method, before injecting sperm into the intracytoplasmic of the oocyte, cumulus cells around the oocyte must be stripped to facilitate the injection process. To achieve this, both enzymatic and mechanical methods are used in embryological laboratories for denudation, which has major deficiencies, including the possibility of damaging the oocyte prior to the injection process. In this research, a microfluidic-based device is introduced for the separation of cumulus cells around the oocyte with minimum manual operations. The results prove high efficiency, and non-destructive denudation of the oocyte with the reduced amount of culture medium leads to the low-cost preparation process of oocytes. The process can also be integrated with ICSI chips under development and will be reported shortly.

Background and Aim: JOB enrichment is a method that has been used to increase employee satisfaction and work motivation. The Hackman and Oldham JOB characteristics model (1976) has served as the foundation for many JOB enrichment efforts. In particular, a considerable amount of research has been devoted to the study of the JOB characteristics-JOB satisfaction relations. Te purpose of this study was to statistically determine the relation between JOB characteristics and JOB satisfaction among employees of hospitals affiliated to Tehran University of Medical Sciences (TUMS) in 2007. Materials and Methods: This study was a cross-sectional one, including 6 TUMS-affiliated hospitals-Emam, Shariati, Baharlo, Ziaeian, Madaen and Azadi. The sample size was 400, consisting of 200 administrative employees (50%), 151 nurses (38%) and 49 physicians (12%). The random sampling and stratified proportional sampling methods were used to select the hospitals and interviewees, respectively. Two questionnaires were developed and used to identify JOB characteristics and JOB satisfaction: 1) JOB diagnostics surveys (JDS) and 2) Hertzberg's JOB satisfaction questionnaire. The reliability of the questionnaires was ascertained by test-retest using the Pearson correlation coefficient (r = 0.88). Linear-by-linear association and ordinal logistics regression analysis were used for analyzing the data gathered.Results:The relations between the Motivational Potential Score (MPS) and JOB characteristics (except for feedback) with JOB satisfaction were statistically significant (p<0.05). Task identity was the most effective determinant of JOB satisfaction. Conclusion: It appears that all the JOB characteristics (except feedback) are important determinants of JOB satisfaction of the hospital employees. Although the work environment is in need of restructuring, it is important to note, from a positive perspective, that the JOB characteristics discussed in this study are readily amenable to change JOB satisfaction at the organizational level.

Purpose: A 12 year-old boy and a known case of JOB’s syndrome presented with a large conjunctival mass which represented coexistence of HPV and HSV infections.Case Report: The presence of HPV virus within these lesions was confirmed by biopsy and DNA analysis. The mass lesions did not respond to anti-HPV therapy with topical interferon-2b, oral cimetidine and oral acyclovir, but improved promptly with antiviral therapy with intravenous acyclovir administered for cutaneous herpetic lesions. HSV infection was diagnosed clinically by the typical extensive epithelial dendritic lesion over the conjunctival mass and its dramatic response to IV acyclovir.Conclusion: Based on our results and on the relevant literature we propose an immunological mechanism for this unique manifestation of coexisting herpes simplex virus and human papilloma virus infections in hyper-IgE syndrome.

One of the issues of reliable performance in the power grid is the existence of electromechanical oscillations between interconnected generators. The number of generators participating in each electromechanical oscillation mode and the frequency oscillation depends on the structure and function of the power grid. In this paper, to improve the transient nature of the network and damping electromechanical fluctuations, a decentralized robust adaptive control method based on dynamic programming has been used to DESIGN a stabilizing power system and a complementary static var compensator (SVC) controller. By applying a single line to ground fault in the network, the robustness of the DESIGNed control systems is demonstrated. Also, the simulation results of the method used in this paper are compared with controllers whose parameters are adjusted using the PSO algorithm. The simulation results show the superiority of the decentralized robust adaptive control method based on dynamic programming for the stabilizing DESIGN of the power system and the complementary SVC controller. The performance of the control method is tested using the IEEE 16-machine, 68-bus, 5-area is verified with time domain simulation.